The main preparation processes for p-tert-butylphenol include the phenol-isobutylene method, the phenol-diisobutylene method, the phenol-tert-butanol method, the C4 fraction method, and the phosphoric acid catalyst method. Among these, the phenol-isobutylene method uses phenol and isobutylene as the main raw materials, adds a cation exchange resin as a catalyst, and carries out an alkylation reaction at a certain temperature, followed by vacuum distillation and other processes to obtain the finished product. The phenol-isobutylene method has a high yield and is the mainstream preparation process in the p-tert-butylphenol industry.
